Archive | Biomedical Autism Intervention

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Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) and Autism

Posted on 06 September 2011 by autism

There is a condition recognized in the biomedical field for autism and related disorders called PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections). This particular condition is caused by an immune reaction triggered by a toxin produced from a Group A Beta-Hemolytic Streptococcal infection. There are various strep bacteria that produce toxins as part of their infectious nature. Our immune system responds to them in an attempt to neutralize and eradicate these toxins. Unfortunately, in some individuals, this immune-toxin (aka. antibody-antigen complex) reaction creates immune complexes which are deposited in various tissues of the body. If these immune complexes land in the kidneys there is an immune reaction called post-streptococcal glomerulonephritis, in the heart it is called rheumatic fever, and in the brain PANDAS can ensue. This autoimmune reaction (self-directed immune reaction to body tissue) in PANDAS is directed to the Basal Ganglia area in the brain. The Basal Ganglia region of the brain when altered or damaged is associated with disorders such as obsessive-compulsiveness (OCD), strange body posturing/movements called chorea, and the typical TIC movements (quick jerking or vocal tics) associated with Tourette’s Syndrome. With obsessive-compulsive behavior anxiety is usually a major problem.

Some individuals on the autism-spectrum suffer with extreme anxiety, but without obsessive-compulsive behavior, while in others the OCD is severe. Even though PANDAS remains a controversial topic in medicine it is reported that PANDAS can cause or exacerbate Tics, Tourettes, and Obsessive-Compulsive Disorder. Approximately, 25% of individuals who have one or more of these conditions have what appears to be PANDAS.

Treatment options are limited, although certain biomedical autism treatments such as low dose naltrexone, dietary intervention such as the gluten and casein-free diet, and various supplements that support normal immune function such as Transfer Factor can be helpful in reducing the overall reactivity of the immune system, PANDAS remains a difficult condition to treat.

Antibiotic therapy has worked for some. I have seen clinically where a short course of antibiotics, such as 10 to 14 days of Keflex, Penicillin or Zithromax definitely helps, particularly with the OCD behaviors. Often times a prolonged course of weekly oral Zithromax has been helpful as suppressing the symptoms of PANDAS. In other situations more advanced biomedical therapies such as intravenous immunoglobulins (IVIG) are needed to short-circuit the autoimmune response. Plasmapheresis, which is a blood cleansing process performed to help diminish the immune-toxin reactions, has shown benefit for some individuals as well. Unfortunately, no treatment is 100% effective for everyone, and some people remain symptomatic even after medical intervention. Great Plains Laboratory – www.greatplainslaboratory.com carries a Streptococcal Panel which highlights immune reactions to strep. If positive this can then be correlated with behavioral and physical manifestations related to PANDAS to see if a treatment trial is indicated.

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Autism Treatmentand the Biomedical Approach – Patience and Perseverance Is Critical For Long-Term Success

Posted on 06 September 2011 by autism

Biomedicine for autism at its roots is a medical approach for treating autism. It is more than just using psychiatric drugs or behavioral therapy. It is the understanding that for most individuals on the autism-spectrum there are underlying medical problems such as intestinal problems, nutritional deficiencies, food allergies, biochemical imbalances and more that contribute directly to their autistic condition.

The implementation of biomedical therapies for individuals with an autism-spectrum disorder is a process of both investigation and patience. The investigative part is determining effectiveness of a therapy versus another. The patience aspect is critical because certain therapies act more quickly than others, and learning to track progress overtime both on a physical and cognitive level is critical. For example, Methyl-B12 therapy (also called Methylcobolamin or MB12) can act very quickly with positive benefits seen in 4 to 6 weeks – in some cases within days. Examples are improved attention, better eye contact and more appropriate speech. On the other hand, a treatment like Hyperbaric Oxygen Therapy – although it can be extremely beneficial – may takeseveral months before positive changes such as better language, more appropriate behavior, and improved immune function are appreciated. In order to implement biomedical autism treatments you have be open-minded and willing to explore new remedies such as dietary changes, supplement therapy, methylation support (through the use of Methyl-B12), detoxification, etc. with your child, and be tenacious in tracking positive and/or negative changes to best ascertain which remedies help the most and which ones are ineffective.

This process of biomedical intervention is not always easy. However, overtime many parents look back at the biomedical approach they have done and know that positive changes have happened. Perhaps their child has more appropriate language, better awareness of their environment and is more engaged socially with family members. Also, a child’s behavior has improved with less self-stimulation, less irritability or complete lack of aggression. Obviously, these are very desirable outcomes.

As a parent implementing biomedical therapies you need to be cognizant of the fact that overtime biomedical therapies will overlap and you will be doing multiple therapies at once. You may reach a point where you’re not quite sure what is working and what is not working. This is a natural trend in any health program and in most situations is unavoidable. At some point, many parents will start to back away from various treatments such as reducing supplements or allowing for periodic gluten and/or milk consumption, etc. to see if any adverse reactions occur. Every person is different and some individuals who have benefitted greatly by biomedical intervention early on are able to handle less rigid programs overtime without losing the positive gains that were made originally.

Biomedicine for autism and learning the various autism treatments takes research and commitment, but the outcomes can be tremendous. Each person’s reaction to biomedical intervention is very individualized. It is not uncommon to expect a few years of consistent and overlapping treatments to be in place before many individuals can have their programs modified. However, know that as a parent or caregiver of someone on the autism-spectrum the biomedical approach to autism is replete with hope and potential for improved health of your loved one.

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AutismTreatment – Digestive, Allergy, and Behavioral Problems

Posted on 06 September 2011 by autism

Ongoing digestive problems such as bloating, constipation, diarrhea, and reflux are often seen in clinical practice with individuals needing autism treatment. Recently, attention has been turned to an opportunistic intestinal infection called Helicobacter pylori (H. pylori). Dr. Amy Yasko has been looking at this bacteria as a contributing factor in autism, and I have seen over the years in certain autistic individuals that Helicobacter pylori is a causative or contributing factor in their persistent problems of food allergies and intestinal dysbiosis. So what is Helicobacter pylori?

H. pylori is a bacterial infection that invades the lining of the stomach and upper intestine. It is commonly associated with ulcer formation, and is a risk factor for stomach cancer. Typically symptoms of H. pylori manifest as pain and pressure in the stomach region, bloating, distention, and reflux disease (heartburn). In individuals on the autism-spectrum these issues may manifest as behavioral problems such as irritability, agitation or self-abusive behavior after eating, poor appetite, avoidance of eating meat, night waking with irritability and self-stimulatory behavior such as chest pounding. Periodically, bad breath not associated with gum disease, and bowel dysfunction such as diarrhea and/or constipation are present.

A common finding in someone dealing with this infection is the need for digestive enzymes and antacids. H. pylori can cause reduction of hydrochloric acid (HCL) production in the stomach leading to the inability to adequately digest food, especially protein. Antacids work by reducing the amount of organic acids that are released by partially digested food, as well as neutralize the stomachs production of HCL. Although there are many natural treatments for H. pylori, it is generally recommended that one use antibiotic protocols to eradicate this organism, while using natural supplements such as garlic, colostrum, mastic gum, and lactoferrin as adjunctive therapy. The use of Matula Tea also seems to have promise against this bacteria as well.

A common mistake with H. pylori testing is inadequate data collection. H. pylori blood testing can be misleading, and most of the medical literature still debates the most effective means of diagnosis. However, I have had good success with diagnosis based on clinical suspicion, patient history, and the use of specific antibody testing. Antibodies are specific immune chemicals that are produced against bacteria, viruses, and parasites. These antibodies are called immunoglobulins (Ig) – IgG, IgM, and IgA. Most medical doctors will only test for IgG against H. pylori sometimes missing the more subtle immune response of the other immunoglobulins. I like to perform all three to increase the yield of detection. I will also perform an H. pylori stool test from BioHealth Diagnostics Laboratory because in certain individuals the Ig blood testing is inconclusive. In children on the autism-spectrum where blood testing is too difficult simply doing the stool antigen test from BioHealth is often enough to detect the presence of the organism.

Helicobacter pylori eradication is an important component in improving overall digestive function as well as total body balance. The human body should always be viewed as a unification of body systems and interrelated physiological function. In autism treatment, this is critical. The traditional medical community needs to move past its archaic viewpoint that autism is purely a neurodevelopmental disorder, and better understand that medical conditions can often be at the root of an autism-spectrum person’s problems.

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Autism Treatment – Is Autism Curable?

Posted on 06 September 2011 by autism

“Autism is curable.” This is a statement some people use to indicate that autism is a disease or health condition that can be overcome. Others have vehemently argued that autism is not a disease process at all, and therefore there is nothing to be cured from. The traditional medical community viewpoint is that there is no cure for autism and only supportive treatment such behavioral modification and drug therapies are options worth pursuing.

To fully understand the concept of cure we need to make a distinction between what is commonly called ‘cured’ (a return to a previous state of health before a change had occurred) and ‘recovery’ (the act of regaining health that was previously lost). Traditional medicine, and even those in the autism medical community realize that there is no known cure for autism, although there are different treatments available including biomedical autism interventions that can help individuals on the autism-spectrum such as diet, i.e. gluten-free and casein-free diet and/or the specific carbohydrate diet, nutritional supplement intervention (including multivitamin/minerals), Methyl-B12 therapy, Respen-A, hyperbaric oxygen therapy, detoxification, anti-fungal treatment, and much more, as well as non-biomedical therapies including applied behavior analysis (ABA), speech and occupational intervention. Traditional medicine even has treatments which are mostly drugs such as Risperdal to suppress aberrant behavior. However, none of these treatments are curative.

I do not use the word ‘cure’ in my consultations, internet postings, lectures, or writings when discussing the various treatments available for individuals on the autism-spectrum. Instead, the more appropriate word I like to use is ‘recover.’ Here is an analogy. If you have an accident and break your arm, and overtime your broken arm heals to the point that movement is restored and it appears indistinguishable from before the accident this would indicate a recovery from your injury. However, your arm would still have suffered the injury and therefore an absolute cure from the accident (and subsequent broken arm) is not possible. You still had the broken arm. However, normal function in your arm has been regained…you recovered!

A similar concept applies to autism. Children (as well as teenagers or adults) are not cured from their autism. However, some individuals can recover, losing their diagnosis, and appear indistinguishable from their peers. In these cases their autism was reversed, most or all symptoms of their disorder have disappeared, and they now function typical of other people, but they will always have had what is classified as autism. So what do you think? is autism curable?

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Autism Treatment – Self-Injury Behavior and Autism

Posted on 06 September 2011 by autism

Self-injury behavior is quite common in autism. I have seen some serious cases where individuals on the autism-spectrum have damaged fingers and hands (from biting) and created deep bruises (from head banging and facial slapping) from self-abusive behavior. There are several theories as to why this occurs, and some resources that can help.

The lack of effective communication skills is likely one of the major reasons for self-injury behavior. The significant language deficits in autism often lead to frustration in a person not being able to communicate their wants or being able to get their point across. The self-abusive behavior such as self-biting can be a way of releasing their frustration. Self-injury can also be a way for an individual on the autism-spectrum to get attention. For example, head-banging or scratching until bleeding occurs will usually draw a parent, therapist or care givers immediate attention. Learning to recognize the different patterns of self-abusive behavior, i.e. the difference between frustration over the inability to communicate versus attention seeking can help in alleviating some of the stress that autistic individuals feel.

Anxiety can be another cause of self-injury behavior. Anxiety in general is high in autism, and if accompanied by self-biting, hitting, slapping, and scratching recognizing the pattern that leads to anxiety, i.e. social gatherings, crowds – then steps can be taken to reduce stressful situations or various treatment intervention, i.e. medication, supplements (GABA, theanine) can be implemented to help ease anxiety.

Recently, studies have uncovered that biochemical changes can occur that contribute to our understanding as to why certain individuals on the autism-spectrum will self-injure themselves. Various chemicals called endorphins are released which influence brain chemistry leading to relief of pain and frustration. In some people these chemicals have a natural calming effect. The improved feelings of calmness may be short-lived, but it does occur. Unfortunately, repeated need to self-abuse is prevalent to induce the endorphin release again. In essence, self-abusive behavior becomes addictive in attempts to get a fix on natural endorphin release for improved sense of temporary well-being.

Some authorities feel that ignoring self-injurious behavior is preferred, but this can be a difficult thing to do for any parent or caregiver. Other reports that learning communication and behavior therapy, possibly along with medication and/or biomedical intervention (diet, supplements) is a better way to proceed. For all family members who are involved in the care of a person with autism learning techniques through communication training is very important. Working with a trained behavior therapist who can help decipher what is causing the self-abusive tendencies can go a long way in eliminating or reducing this troubling behavior.

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Autism Treatment – Chronic Stress and Autism

Posted on 06 September 2011 by autism

Everyone experiences stress in their lives. What separates one person from the next is how their body adapts to stress. Not all stress is bad, as stress can have its benefits in helping the body react, grow and adapt such as building a vibrant immune system. However, chronic stress can lead to long-term health consequences. Stress can come in many forms. Environmental changes such as cold, heat and extreme weather is a form of stress. Foods and food allergies are a form of stress. Mental and emotional factors are a major cause of stress in many people. Parents of autistic children experience a tremendous amount of mental and emotional stress in having to take care of a special needs child.

Vaccines are a form of stress that pushes the immune system to produce protective immune chemicals against vaccine related illnesses. Unfortunately, at times these reactions go array and lead to biochemical imbalances in the body and brain. Hormone imbalances, digestive problems, immune system dysfunction, metabolic disorders can all occur from a chronic burden of stress. Even children respond to stress in similar ways as adults with many of them experiencing mental/emotional changes such as depression, anxiety, and fear.

Children on the autism-spectrum experience stress in a profound way. Cognitive decline, lack of speech, anxiety, lack of social connections, and other behavioral manifestations are a form of mental/emotional stress. In my experience autism-spectrum children are dealing with a lot of physical challenges as well, many of which contribute and worsen their already declining cognitive abilities. Digestive disorders like diarrhea, constipation, yeast and bacterial infections cause a tremendous amount of toxicity in the body. This can cause pain, headaches and a feeling of overall sickness. Immune dysfunction in many children predisposes them to opportunistic infections such as viral, bacterial and yeast imbalances.

Food allergies and sensitivities play a big role in chronic illness. With autism many individuals are burdened with multiple food sensitivities. This leads to bloating, gas, diarrhea, constipation, and malabsorption – all common in autism. Malabsorption (difficulty in absorbing nutrients from the digestive tract into the blood stream) leads partly to the epidemic of nutritional deficiencies seen often in autistic children. Some of these nutritional deficiencies like iron and B-vitamins can lead to anemia causing fatigue, blood cell abnormalities and immune problems. In short, most autism-spectrum children are dealing with various forms of stress in their lives, and much of this stress is interfering with their ability to get well.

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Biomedical Autism Treatment – Respen-A blended chord, Inositol and Autism part 2

Posted on 01 August 2011 by autism

This is part 2 of the 2 part series on Respen-A blended chord and inositol. So inositol has been around for a long time and has been recommended in the past for OCD and anxiety. In some kids it works great, others it doesn’t work at all. And unfortunately it has been seen some kids who have reacted negatively to just the straight use of inositol. It probably likely has to do with the fact that its having an effect on glucose sugar metabolism in the brain and bolstering serotonin release. But up until recently, I mean we are talking the past couple of years, there wasn’t a lot known about how serotonin was metabolized in kids on the Autism spectrum.

We know now through the work of Elaine DeLack and the research through the Respen-A people that the Monoamine Oxidase A tends to be a problem area for many kids on the spectrum and therefore something like Respen-A has been a useful remedy to use, and I have seen that clinically in my practice as well. So just some information if you are looking to do the Respen-A blended chord it is now recommended that inositol be used along with it. And then if you want to find out more information specifically, obviously it comes with the Respen-A when the prescription comes from the dosing instructions. You can also access Respen-A on Facebook and I also have information on autismactionplan.com in the biomedical protocol section of that website. And I am of course available on an ongoing basis through the parent forum of autismactionplan.com to just answer your questions on a daily basis.

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Autism Treatment – Spring Allergies, Regression and Autism part 2 of 2

Posted on 12 May 2011 by autism

In our first article we discussed the yeast overgrowth that can come in the spring time and why this happens. Now we will talk about more ways to address this if it happens. The other thing is you can do in autism treatment some different types of supplements to help if your child is susceptible to allergies, things like vitamin C, stinging nettles, bromelain, quercetin, N-acetyl cysteine, can be helpful. New Beginnings Nutritionals carries something called an A and I formula which is an allergen inflammation formula you can go right to their website, order that and it has dosing recommendations right there. That can be something that can be used not only for acute allergies but for maintenance therapy too.

Autism Treatment for Spring Allergy and Regression

If yeast is occurring, then of course then doing the things that we know for yeast, prescription wise Nystatin, Diflucan, Lamisil, Nizoral, etc. of course you need a prescription for those. Or there’s natural remedies too. Again New Beginnings carries a yeast formula packet which is a combination of four different remedies you can rotate anywhere from five to ten drops twice daily for five days and then rotate through those different supplements. Grapefruit seed extract five to eight drops two to three times a day can be helpful for yeast. Candex is another type of supplement, it’s an enzyme that helps to break down the cell wall of yeast, there’s a combination of things. I tend to see good results with things like grapefruit seed extract and the yeast formula packet that New Beginnings carries.

If the supplements are not holding the allergies then sometimes even just a short course of an allergy medication, Claritin over the counter can be helpful Singulair as a prescription can be helpful, you can talk to your pediatrician or family physician about that. Even if it’s just for four to six weeks to get through the real intense period of spring. So again, in autism treatment in spring, it can bring on yeast behavior, I’ve seen it I’m already seeing it again this year, just be aware of it.

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Autism Treatment – Chemical Exposure and Treatment in Autism Part 1 of 2

Posted on 10 May 2011 by autism

Autism Treatment – We’re all exposed to chemicals and chemicals are a natural part of our world anymore with the modern homes, the technology that we have, and so in many respects we can’t escape chemical exposure a hundred percent. We do know that for many kids on the Autism spectrum they tend to be very chemically sensitive. Their detoxification pathways are poor, many times their biochemistry is being upset because of nutritional deficiencies or yeast or bacterial overgrowth, digestive imbalances, all that can put a strain on their body. And so any time that there’s a chemical exposure, some kids, not all, but some kids can react adversely. Whether it’s self stimulatory behavior, irritability, agitation, poor sleep, poor behaviors etc. if they’ve had some type of acute chemical exposure.

Chemical Test With Autism Treatment

Now, there’s all kinds of different tests that you can do for chemicals, some are easy, some aren’t not necessarily all are affordable either, or even really necessary. If you take the approach of just trying to improve your lifestyle factors as far as exposures you could do a lot to decrease chemical exposures particularly in your home. For example, using biodegradable, non-scented laundry detergent, instead of using the conventional detergents, you can actually now get laundry detergent that is non-scented, biodegradable and is more natural than some of the more synthetically derived forms. Same thing with water, using purified water, filtered again is another way of reducing chemical exposure. Using organic food, hormone free, anti-biotic free meats again is a way to decrease overall chemical exposure. You’re not going to be able to avoid things a hundred percent depending on where you live, if you’re in a city there’s going to be smog, if you’re in the country there could be farming so things are going to be sprayed, you’re going to have some exposure on a daily basis.

One of the things that can help as an autism treatment, if your child has been exposed to chemicals, or you’re concerned about it, is simply doing Epsom salt baths. Now, Epsom salt is magnesium sulfate, the magnesium is a relaxing element mineral for the body the sulfate actually helps to support detoxification. Sulfur chemistry in the body is critical for the maintenance of connective tissue but it’s also critical for the way our body helps to release and get rid of toxins. So Epsom salt baths have been a great way to support detoxification. In the second half of this series we will talk more about ways to implement Epsom salt baths into your child’s protocol to help in detoxification of chemicals.

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Autism Treatment – Regression, Gut Problems and Autism Part 2 of 2

Posted on 09 May 2011 by autism

Autism Treatment – And what I’ve seen in having these kids, I wish I could do more, but in having had many of these kids evaluated by doing intestinal scoping through a gastro-enterologist is you will often find inflamed guts and what is characteristic of Autistic enterocolitis. Now, the main doctor I refer people to from a pediatric gastroenterologist is Dr. Krigsman who’s in Texas. He’s been my sort of go-to doctor for these types of assessments now for years. The reality is in my experience there just aren’t a lot of doctors around who are willing to evaluate kids on the spectrum from a GI perspective to level that they need to be evaluated and really understand the complexities of it. And what I’ve seen through doctor Krigsman’s assessments is that these children have inflamed guts, sometimes quite significant, but kids have an amazing ability to compensate for pain.

Gut Problems with Autism Treatment

So they’re not all manifesting with extreme pain or distress. We just have this cyclical nature of improvement, this waxing and waning effect of improvement then worsening, improvement and worsening, and over and over and over. Many times it very characteristic of Crohn’s disease which can tend to have a waxing and waning effect. If you have a child that you’re suspicious that this may be going on actually go and read about Crohn’s disease in kids. I think what you’ll see is you’ll see a lot of things in the classic description of Crohn’s autism treatment that tends to fit the bowel patterns of many kids on the Autism spectrum. So I wanted to make you aware of that because it’s something that I realize it’s frustrating and it’s an ongoing battle but if you’ve been battling this over and over and over for months if not years then I really encourage you to look to have your child evaluated from a pediatric gastroenterologist specialist who is familiar with the complexities of Autism to see about what exactly is going on in your child’s gut.

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"When my daughter was diagnosed with Autism 3 years ago I would have done anything to have something like the Autism Action Plan to turn to. Doctors diagnose your child like she has a cold and give you no information on what it is or how to help your child. I spent the first year after my daughter was diagnosed researching anything and everything I could about autism. I didn't find even a fraction of the information that is provided in Autism Action Plan. Everything is all right there, current research and therapies, the ability to talk with other parents dealing with the same struggles you face, and most importantly, direct contact with a caring doctor who has dedicated his career to treating our children. Whenever I meet anyone who has or knows a child with autism, I tell them about this wonderful service and encourage them to get plugged in. It is a valuble resource for parents and we are very thankful for it."
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